Tamoxifen Citrate (Nolvadex)
Description : Tamoxifen Citrate (Nolvadex) is very comparable to Clomid (Clomephine), the fertilization drug and behaves the same way in all bodily tissues. Tamoxifen is a mixed estrogen agonist/antagonist of the same type as Clomid. The two molecules are also very similar in structure.
Tamoxifen is the standard endocrine (anti-estrogen) therapy for hormone-positive early breast cancer in pre-menopausal women along with other aromatase inhibitors Because some breast cancer cells require estrogen to grow, the estrogen binds to the estrogen receptor in these cells.
Tamoxifen is metabolized into compounds that bind to the estrogen receptor but do not activate the recpetor. Tamoxifen rather, acts like a jam in a lock that prevents any other key from being inserted into it. Tamoxifen effectivley prevents estrogen from binding to its receptor and breast cancer cell growth is likewise blocked in breast tissue that.
Tamoxifen was discovered by AstraZeneca™ and sold under the trade names Nolvadex™, Istubal™, and Valodex™.
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